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MSE™ (Multiple
Stabilized Enzymes)
contains
various enzymes
including:
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protease lipase cellulase
amylase (mainly
a-amylase)
lactase
glucase phytase
maltase (a-glucosidase
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Also included in MSE are
numerous strains of
yeast, fungi and
bacteria. In addition, MSE contains crucial
vitamins and minerals,
as well as detoxifiers.
WHAT MSE DOES:
The major advantage of
using MSE is to increase
the digestibility of
food. MSE can increase
the digestibility by
8-10% in ruminants
(animals having 3 or 4
stomach compartments) and
12-14% in monogastrics
(animals with one
stomach compartment).
This means swine can
gain the same amount on
12-14% less feed. This
increase in
digestibility also means
that the animals absorb
more
vitamins and minerals. With
less waste being
produced, there is
consequently less stool
matter
and less undegrated
material in the stools.
That means less odors!
The bacteria, fungi and
yeast included in MSE
also provides your
animal with a probiotics
source. Probiotics (now
termed DFM's) are
beneficial in increasing
digestion factors and
acting as a safe-guard
during times of stress.
The following article
gives an explanation on
the importance of DFM's
and compares them to
antibiotics.
With the widespread
availability of
antibiotics over forty
years ago, antibiotic
feeding became a common
practice for use as a
therapeutic agent and a
growth stimulant for
livestock. Since their
introduction, however,
there has been a growing
concern about the use of
antibiotics resulting in
the development of
resistant strains of
bacteria, which made
subsequent use of
antibiotics less
effective. This later
resulted in the banning
of most antibiotics as
growth promoters in
animal feed supplements.
There has also been much
public concern over the
use of antibiotics, due
to the possibility of a
residue left in meat.
Today, only the disease
preventive antibiotics
are allowed and they are
widely used for this
purpose.
These oral antibiotics
have been shown to cause
intestinal upsets after
ingestion, despite their
effectiveness for curing
the disease for which
they have been
prescribed. These
intestinal upsets are
usually caused by the
disruption and death of
the beneficial bacterial
flora, as a result of
the antibiotic.
Therefore, full
recovery is slowed
or even prevented with
disease treatment by an
antibiotic.
These factors have led
to the search for
alternatives to feeding
antibiotics. Probiotics
are being considered to
fill this role, and many
producers are already
using them in preference
to antibiotics. The word
"probiotic" has come to
have an elusive meaning.
One satisfactory
definition is, "a living
microbial feed
supplement which
beneficially affects the
host animal by improving
its intestinal microbial
balance." In 1989,
however, the FDA
required manufacturers
to use the term
direct-fed microbial
(DFM) rather than
probiotic. The FDA
defines DFM as "a source
of live (viable)
naturally-occurring
microorganisms." This
definition includes
bacteria, fungi, and
yeast.
The
entire mode of action of
DFM's is not wholly
known. Its general
effects, however, are
simple - especially when
compared to antibiotics.
Antibiotics function via
the destruction of
pathogenic organisms in
an animal's digestive
system. In other words,
an antibiotic kills
microbial life in the G.I. tract in an effort to
destroy pathogens. The
problem with this is
that many of the
beneficial
microorganisms are
killed in addition to
pathogenic organisms.
This can be very
detrimental since the
beneficial
microorganisms are the
animals principal defence mechanisms
against pathogens, as
well as being important
in the digestive
process. This loss of
these microbes creates a
stress factor on the
animal and slows
recovery until these
beneficial
microorganisms regain
their population.
On the other hand,
direct-fed microbials
actually add live
(viable), beneficial
organisms to an animal's
system. These organisms
increase the health of
an animal's system in
several different ways.
To develop an
understanding, one
should know the purpose
of the gut microflora
(digestive tract
microorganisms).
Digestive tract
microflora aid the
animal in digesting feed
and aid to resist
infections naturally by
competing with and
fighting against
pathogens while serving
to protect the G. 1.
tract walls. This is
shown best by the fact
that germ-free animals
are more susceptible to
disease than are normal
animals with a complete
intestinal microflora.
For example, whereas a
germ-free mouse can be
killed with 10 cells of
Salmonella enteritidis,
1,000,000 cells are
required to kill a
conventional mouse.
Taking this into
consideration, one can
easily see the risk of
recovery from a mostly
absent microflora due to
the feeding of an
antibiotic, since an
antibiotic tries to
remove pathogens instead
of naturally increasing
the animals health and
resistance to these
pathogens
Using the aforementioned
information, it is
evident that the
presence of microflora
greatly decreases an
animal's chance of
getting sick; but why is
this so? Some possible
modes of action of DFM's
include:
1.Suppression of
infectants by:
a. production of
antibacterial compounds
b. competition for
nutrients
c. competition for
adhesion sites
2. Alteration of
microbial metabolism by:
a. increased
enzyme activity
b. decreased
enzyme activity
3. Stimulation of
immunity
a. increased
antibody levels
b. increased
macrophage activity
Besides the factors
mentioned that generally
increase the state of
health of an animal,
DFM's have been shown to
affect many other
aspects such as passage
rate, digestibility,
rate of gain, milk
production, etc....
With continual feeding,
DFM's have been shown to
maintain herd health
without the side effects
that are present when
using antibiotics. A
feeding program
involving a continual
supply of DFM's to an
animal results in a
stronger and healthier
gut microflora. This
yields an animal that is
less susceptible to
illness and disease.
Also, if the treatment
of an animal with a DFM
is plausible, there are
fewer or no side effects
as compared to an
antibiotic. In addition,
Aspergillus oryzae
(A.O.) and Sacharomyces
cerevisiae (S.C.)
cultures have been shown
to increase fiber
digestion and milk
yield. Other possible
benefits include
increased rate of
passage, rate of
fermentation, DM
digestibility, CP
digestibility, ADG and
total VFA production.
Decreases include a
lower feed: grain ratio
and less methane
production. Use of other
microbials and microbial
by-products, such as
bacteria and enzymes,
can aid in the digestive
process even further.
When it is necessary to
treat an animal with an
antibiotic, DFM's are
especially beneficial as
an aid to reduce stress
and boost the animal's
microflora population
back to normal for a
speedy recovery.
This is where Natur's
MSE enzyme feed
additive comes into
play. In addition to the
multiple enzymes
included for increased
feed conversion, MSE
also contains more
active microbials than
many DFM products. These
microbials include
multiple strains of
bacteria, yeast and
fungi. Therefore, MSE is
not intended to merely
increase digestibility,
but it also adds crucial
microbes (DFM'S) to
stabilize and increase
the health of the G. I.
tract.
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